Pitolisant oxalate
CAS No. 362665-57-4
Pitolisant oxalate ( Tiprolisant oxalate )
Catalog No. M14245 CAS No. 362665-57-4
A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM; no effect on H1, H2, H4 receptors (IC50>10 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 873 | Get Quote |
|
50MG | 1782 | Get Quote |
|
100MG | 2250 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NamePitolisant oxalate
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NoteResearch use only, not for human use.
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Brief DescriptionA potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM; no effect on H1, H2, H4 receptors (IC50>10 uM).
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DescriptionA potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM; no effect on H1, H2, H4 receptors (IC50>10 uM); orally bioactive.Sleep Disorder Approved
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SynonymsTiprolisant oxalate
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorHistamine Receptor
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Research AreaNeurological Disease
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IndicationSleep Disorder
Chemical Information
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CAS Number362665-57-4
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Formula Weight385.88
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Molecular FormulaC19H28ClNO5
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESC1CCN(CC1)CCCOCCCC2=CC=C(C=C2)Cl.C(=O)(C(=O)O)O
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Chemical NamePiperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-, ethanedioate (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ligneau X, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):365-75.
2. Dudek M, et al. Metab Brain Dis. 2016 Oct;31(5):1023-9.
3. Ligneau X, et al. Biochem Pharmacol. 2007 Apr 15;73(8):1215-24.
2. Dudek M, et al. Metab Brain Dis. 2016 Oct;31(5):1023-9.
3. Ligneau X, et al. Biochem Pharmacol. 2007 Apr 15;73(8):1215-24.
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