Pitolisant oxalate ( Tiprolisant oxalate )

Catalog No. M14245 CAS No. 362665-57-4

A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM; no effect on H1, H2, H4 receptors (IC50>10 uM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	873	Get Quote
50MG	1782	Get Quote
100MG	2250	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Pitolisant oxalate
Note

Research use only, not for human use.
Brief Description

A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM; no effect on H1, H2, H4 receptors (IC50>10 uM).
Description

A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM; no effect on H1, H2, H4 receptors (IC50>10 uM); orally bioactive.Sleep Disorder Approved
Synonyms

Tiprolisant oxalate
Pathway

GPCR/G Protein
Target

Histamine Receptor
Recptor

Histamine Receptor
Research Area

Neurological Disease
Indication

Sleep Disorder

Chemical Information

CAS Number

362665-57-4
Formula Weight

385.88
Molecular Formula

C19H28ClNO5
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

C1CCN(CC1)CCCOCCCC2=CC=C(C=C2)Cl.C(=O)(C(=O)O)O
Chemical Name

Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-, ethanedioate (1:1)

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ligneau X, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):365-75.
2. Dudek M, et al. Metab Brain Dis. 2016 Oct;31(5):1023-9.
3. Ligneau X, et al. Biochem Pharmacol. 2007 Apr 15;73(8):1215-24.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks